Hey all! Thank you Q!
The update.df2.exe should do the trick, likely you'll want to click the 4 corner buttons, Update, Nlpatch, vista fix and nocd. You can also get a slew of other updates if you want to try them w/o the update.df2 patch at DF2Central (http://df2central.sbccrew.com/downloads.php).
I'm yet to meet someone that can't run df2, whether it be win98 or win7.